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Pseudoephedrine (Afrab-Chem)

Afrab-Chem Ltd
No. 22, Abimbola Street, Isolo Industrial Estate, Isolo, P.O. Box 1647, Lagos, Nigeria.
Email: info@afrabchem.com
Tel: 234-1-2700057
Fax: 234-1-4520328
Website: http://afrabchem.com/

Brand Name

Pseudoephedrine (Afrab-Chem)

Manufacturer

Afrab Chem Limited, 22 Abimbola Street, Isolo Ind. Est., Isolo, Lagos.

Therapeutic Class

Nasal preparations, Systemic

Dosage Form, Composition & NAFDAC Registration Number (NRN)

Tablet (NRN:A4-7566): Pseudoephedrine HCl 60 mg.

Pack size: A blister satchet of 10 Tablets.

Pharmacology

Pseudoephedrine is a direct- and indirect-acting sympathomimetic agent with less pressor activity and central nervous system effects. It acts as an oral vasoconstrictor for nasal decongestion.

Indications

Pseudoephedrine is used for symptomatic relief from nasal stuffiness due to colds, from irritation and inflammation of the nose and throat due to hay fever.

Contra-indications

In patients sensitive to Pseudoephedrine. Hypersensitivity to sympathomimetic amines; severe hypertension; coronary artery disease; MAOIs therapy; breast-feeding mothers.

Precautions/Warnings

Pseudoephedrine should be used with great caution in patients with hypertention, hyperthyroidism and enlargement of the prostate. Great care is also needed in pregnancy, breastfeeding and persons over 65 years of age.

Interactions

Furazolidone, guanethidine, methyldopa: Increased BP.

MAOIs: Severe headache, hypertension and hyperpyrexia; can cause hypertensive crisis.

Urinary acidifiers (eg, ammonium chloride): Increased elimination of pseudoephedrine.

Urinary alkalinizers (eg, sodium bicarbonate): Decreased elimination of pseudoephedrine.

Adverse Effects

Occasionally dryness of the mouth, loss of appetite, restlessness, insomnia, acceleration of the pulse, palpitation.

Dosage & Administration

Adult and children over 12 years: 60 mg three to four times daily.

Children below 12 years: Not recommended

Or as directed by the Physician.

Storage/Handling Recommendations

Store protected from light.

Keep in a cool dry place and away from children.

Review Date

2017-09-30 02:46:43