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Tri-Eco-G Cream

Solutions Pharmaceuticals Nig. Ltd.
16 Nnobi Street, By Kilo B/stop, Surulere lagos.
Email: solutionsph@yahoo.com, solutionspharm@yahoo.com
Tel: 08023102841, 08099931251, 07054679238.

Brand Name

Tri-Eco-G Cream

Manufacturer

S Kant Healthcare. 1802-1805 GIDC Phase III, Vapi396195 Gujarat India.

Therapeutic Class

Anti-infective/Corticosteroid combinations, Skin

Dosage Form, Composition & NAFDAC Registration Number (NRN)

Cream (NRN: A4-7538): Econazole Nitrate BP 1%w/w, Triamcinolone Acetonide 0.1%w/w, Gentamicin Sulphate BP (equivalent to Gentamicin) 1%w/w.

Pack Size: 30g Aluminum collapsible/lami tubes.

Pharmacology

Tri-Eco-G is an antifungal, antibiotic and anti inflammatory cream . It contains an azole, aminoglycoside and a corticosteroids. This presents varied pharmacological properties.

Econazole and Triamcinolone are readily absorbed through the skin while Gentamicin is poorly absorbed. Because of the risk of super-infection, usage should be limited to confirmed mixed infections.The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear.

Pharmacokinetics:

The extent of percutaneous absorption of Tri Eco G is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings. Topical corticosteroids can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption. It is metabo lized in the liverand excreted through the kidney.

Indications

Tri-Eco-G is used in the treatment of skin infections due to susceptible organisms including dermatophytes, tricophytons, yeast, candida and gram positive bacteria. It is used to treat skin infections such as atlethes foot, jock itch, ringworm and other fungal skin infections (candidiasis).

This medication is also used to treat a skin condition known as pityriasis (tinea vesicolor), a fungal infection that causes a lightening or darkening of the skin of the neck, chest, arms, or legs.

Also used in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum.

Contra-indications

Tri-Eco-G is contraindicated in patients that have previously shown hypersensitivity reaction(s) to any of the active components or any excipients of the cream.

Precautions/Warnings

Serious allergic reactions to Tri-Eco-G is unlikely but immediate medical attention should be sought in the event of any untoward reaction.

Symptoms of a serious allergic reaction may include: rash.

Caution should be applied in administering to pregnant women, nursing mothers and children below the age of 12 years.

FOR EXTERNAL USE ONLY.

Interactions

No known interaction that is considered serious.

Adverse Effects

During clinical trials, approximately 3% of patients treated with econazole nitrate 1% cream reported side effects thought possibly to be due to the drug, consisting mainly of burning, itching, stinging and erythema. One case of pruritic rash has also been reported.

Dosage & Administration

Apply thoroughly to the affected areas, two times daily after bath. Massage gently until white cream disappears.

Overdosage:

Accidental ingestion will require supportive care. Tri-Eco-G used topically has a very remote chance of over dosage of clinical importance. Nevertheless, over exposure may give rise to systemic effects of the individual components.

Storage/Handling Recommendations

Store in a cool dry place away from light at a temperature not more than 25ºC.

Review Date

2017-01-24 11:01:26