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Clearex 10

Pemason Pharmaceuticals Limited
72 Agege Motor Road, Alakara, Mushin.
Email: pemas80@yahoo.com
Tel: 01-81507361, 2663986, 234-8033018912, 08033054541

Brand Name

Clearex 10

Manufacturer

Medline/Medibrands Ltd., Hamada 6 st., Yokneam 20692, Isreal.

Therapeutic Class

Anti-acne preparations, Topical

Dosage Form, Composition & NAFDAC Registration Number (NRN)

Lotion (NRN: 04-5202): Benzoyl peroxide 5% w/w, 10% w/w.

Inactive ingredients: Glycerin, xantham gum, silica colloidal carbomer 934P, Hydrochloric acid, sodium hydroxide, edetate disodium, sodium citrate, citric acid, purified water.

Pack size: 1's

Clearex

Pharmacology

The mechanism of action of benzoyl peroxide is not totally understood but its antibacterial activity against Propionibacterium acnes is thought to be a major mode of action. In addition, patients treated with benzoyl peroxide show a reduction in lipids and free fatty acids, and mild desquamation (drying and peeling activity) with simultaneous reduction in comedones and acne lesions.

Little is known about the percutaneous penetration, metabolism, and excretion of benzoyl peroxide, although it has been shown that benzoyl peroxide absorbed by the skin is metabolized to benzoic acid and then excreted as benzoate in the urine. There is no evidence of systemic toxicity caused by benzoyl peroxide in humans.

Indications

This medicine is indicated for the treatment of acne pimples.

Contra-indications

Do not use this medicine if you are sensitive to any of its ingredients. Do not use this medicine without consulting a doctor before starting Treatment if you are pregnant or breast feeding.

Precautions/Warnings

Do not use this medicine frequently or for a long period without consulting a doctor. If you are sensitive to any type of food or medicine, inform your doctor before using this medicine.

Do not use if you have an inflamed or sensitive skin.

Attention:

This medicine is for external use only.

Avoid contact of this medicine with eyes, lips and mouth.

This medicine may bleach hair and colored clothes.

Interactions

If you are using another drug concomitantly or if you have just finished treatment with another medicine, inform the doctor in order to prevent hazards or lack of efficacy arising from drug interactions.

This is especially important with medicines belonging to the following groups: other topical acne treatment medicines or any other cosmetic that may dry out your skin.

Adverse Effects

In addition to the desired activity of the medicine adverse reactions may occur during use. For example: mild burns, flushing, redness, rash, itching, dryness of the skin.

Effects that demand a special consideration: long lasting rash, swelling of the face, excessive peeling. If those happen, stop immediately the use of the medicine and consult your doctor. Therefore it is recommended to do a test of sensitivity before using this medicine, by applying it to a small affected area once a day for two days.

If undesired effects appear, do not use this medicine. Consult your doctor. If no discomfort or burning occurs, follow label instructions and continue use.

Undesired side effects generally disappear within a short time of adaptation to this preparation.

Do not exceed the recommended dose. This medicine is not intended for administration to children I infants under 12 years of age.

Dosage & Administration

Wash skin thoroughly and dry well. Apply a small quantity of the lotion once a day initially, and then two or three times a day or as directed by the physician.

If there is no significant improvement within 4 to 6 weeks, consult your doctor.

Storage/Handling Recommendations

Store in a cool place. Even if kept in their original container and stored as recommended, medicine may be kept for a limited period only. Please note the expiry date of the medicine.

If any case of doubt, consult the pharmacist who dispensed the medicine to you

Do not store different medications in same package.

Review Date

2015-07-08 08:06:02