13B, Sunny Jigide Street, Off Celestial Way, Ogudu, Lagos; 57, Isheri Rd, Aguda, Ogba, Ikeja, Lagos.
Email: email@example.com; firstname.lastname@example.org
Tel: 234-1-815-065-1200; 234-1-815-065-1199; 815-506-1205
Jewim pharmaceutical (shangdong) co. Ltd. Tai’an High-tech Industrial Development Zone, Shangdong Province, China.
Dosage Form, Composition & NAFDAC Registration Number (NRN)
Spray (NRN: ): Each 1 mL of the 60 mL solution contains 2% of Minoxidil.
Pack Size: Alorepair spray 2% minoxidil is available in a bottle of 60 mL.
When applied topically, ALOREPAIR topical solution has been shown to stimulate hair growth in individuals with alopecia androgenetica (male pattern baldness).
Although the exact mechanism of a ction of ALOREPAIR in the treatment of alopecia androgenetica is not known, there may be more than one mechanism by which minoxidil stimulates hair growth; they include: vasodilation of the microcirculation around the hair follicles which may stimulate hair growth;
direct stimulation of the hair follicle cells to enter into a proliferative phase: resting phase (telogen) follicles being stimulated to pass into active phase (anagen) follicles;
alteration of the effect of androgens on genetically predetermined hair follicles: minoxidil may affect the androgen metabolism in the scalp by inhibiting the capacity of androgens to affect the hair follicles.
ALOREPAIR is a topical solution for the treatment of alopecia androgenetica (male pattern baldness of the vertex of the scalp and in females as diffuse hair loss or thinning of the frontoparietal areas). It promotes hair growth and the epithelium of hair bursa.
The response is better when the patients use ALOREPAIR directly after hair loss. At least four months of twice daily applications are generally required before evidence of hair growth can be expected.
If patient respond to treatment, he will need to continue using ALOREPAIR to maintain hair growth. In the treatment of alopecia androgenetica (male-pattern baldness) 1 mL of a 2% or 5% solution of ALOREPAIR is applied twice daily to the scalp. The 5% solution is not recommended for women.
ALOREPAIR is contraindicated in patients with Arterial hypertension, who are hypersensitivity to minoxidil, propylene glycol or ethanol and any other component of the preparation, pregnant and lactating.
Local abrasion or dermatitis of the scalp may increase absorption and hence increase the risk of side effects;
patients with history of or existing heart disease should be advised of potential serious adverse effects;
observing patients for tachycardia and fluid retention;
patients should be monitored for increased heart rate and weight gain or other systemic effects (discontinue use if systemic effects occur);
avoid use in pregnancy, lactation and children below 18 years of age;
avoid contact with eyes and any irritated skin (wash with large amount of water if ALOREPAIR gets into the eyes, mucous membranes or sensitive skin areas).
Do not apply on other parts of the body and stop use when changes in hair colour and texture is noticed.
Avoid co-administration with other topical agents including topical corticosteroids, retinoids, and petrolatum or agents that are known to enhance cutaneous drug absorption. Avoid administration with guanethidine. Ask a doctor before use if you have a heart disease.
Most commonly, itching and other skin irritations of the treated area of the scalp. Infrequent adverse reactions including allergic reactions (sensitivity, hives, generalized erythema and facial swelling);
dizziness; tingling sensation; headache; weakness; neuritis; oedema; eye irritation; altered taste; ear infection (otitis externa); and visual disturbances have been reported.
Rarely reported adverse reactions included alopecia, hair abnormalities, chest pain, blood pressure changes, pulse changes, hepatitis, and kidney stones.
Dosage & Administration
ALOREPAIR is for external use only.
Use only as directed.
A total dose of 1 mL minoxidil topical solution should be applied twice per day to the scalp, beginning at the centre of the affected area.
This dose should be used regardless of the size of the affected area.
The total daily dose should not exceed 2 mL. Put the tip of the sprayer on the affected area of the dry scalp and press it once to apply 1 mL solution as a thin film twice daily at 12 hour intervals to the centre of the bald areas and spread with massaging movements to cover the entire affected area; 4 months or more maybe necessary for hair regrowth.
After applying ALOREPAIR topical solution, wash hands thoroughly.
Do not apply the topical solution to any other area of the body.
Apply ALOREPAIR topical solution when the hair and scalp are thoroughly dry.
Do not use a hairdryer to speed the drying of the topical solution, because blowing air on the scalp may decrease the effectiveness of the drug.
SYMPTOMS AND TREATMENT OF OVERDOSAGE:
The symptoms include Itching and skin irritation. Washing the area with large amount of water and reducing the dosage.
Flammable: keep away from fire or flame.
Storage: Store at a temperature less than 30oC.
Shelf life: 3 Years.