Doppelherz Aktiv Calcium + D3

Agary Pharmaceutical Limited
Plot C39A, Amuwo Odofin Commercial Scheme, Along Alakoso Avenue, Amuwo Odofin, Lagos.
Tel: 0809-275-6424, 0809-275-6425, 0808-745-4848.

Brand Name

Doppelherz Aktiv Calcium + D3


Queisser PHARMA GmbH & Co.
KG schleswiger Str. 74 24941 Flensburg Germany

Therapeutic Class

Vitamin/Mineral supplements

Dosage Form, Composition & NAFDAC Registration Number (NRN)

Tablet (NRN: B4-4191): • Ingredients: Calcium Carbonate, Bulking agent: Starch, Bulking agent: cellulose, Anti-caking agent: Silica, Stabiliser: Hydroxypropyl methyl cellulose, Anti-caking agent: Magnesium salts of fatty acids, thickner: Cross-linked sodium carboxy methyl cellulose, Colour: titanium dioxide, Anti-caking agent: Cellulose, Glazing agent: fatty acids, Cholecalciferol (Vitamin D), Phytomenadione (Vitamin K).

Pack Size: 3 × 10’s (Tablet in blisters); • Energetic Value: 1 tablet corresponds to 1 kcal/ 4 KJ

Nutritional information PER SERVING
Calcium 600 mg
Vitamin K 40 µg
Vitamin D3 5 µg

Doppelherz aktiv calcium  D3 


Calcium is the most abundant mineral in the human body. Calcium plays a very important role in the body. Calcium is involved in muscle contraction, neurons activity and blood coagulation. The Calcium, Vitamins  D3 and K combination is essential for healthy bones, muscles and nerves. Vitamins D3 and K are involved in complex pathways that make calcium function optimally.

• From the food to the blood: Dietary calcium is absorbed by a specific transporter which is stimulated by Vitamin D3. Also, Vitamin D3 helps to balance Calcium and phosphate in the blood as required for bone formation.

• Vitamin D3 aids in the maintenance of calcium homeostasis (dynamic control of circulating Ca levels by regulating assimilation / use / storage / mobilization). It regulates calcium uptake into the bones. Vitamin D acts on the intestinal calcium transporter to stimulate calcium absorption and on the parathyroid gland and on the kidneys to regulate circulating calcium levels.

• From the blood to the bone: Calcium is brought into the bone matrix by proteins like Osteocalcin. This is only possible if osteocalcin has been activated through post translational carboxylation, a reaction dependent on Vitamin K. Adequate amounts of vitamin K2 are needed in order to activate osteocalcin – the protein circulating in the blood, which is responsible for binding calcium ions to the matrix of bone, making bones stronger.

• The Calcium, Vitamin D3 and Vitamin K present in this Doppelherz® aktiv tablets constitute the ideal combination to reach recommended daily intake of Calcium and ensure an optimal Calcium integration into the bones.


Osteoporosis, postmenopausal women and weak bones (osteomalacia)


Patients using blood thinners such as warfarin.


Adhere to the stated dosage.


Some products that may interact with this drug include: digoxin, phosphate binders.

If taken at the same time with other drugs, Calcium can decrease the absorption of other drugs such as tetracycline antibiotics (e.g., doxycycline, minocycline), bisphosphonates (e.g alendronate), estramustine, levothyroxine, and quinolone antibiotics (e.g., ciprofloxacin, levofloxacin).

Vitamin D is an oil soluble vitamin, their absorption can be decreased and the excretion rate can be increased by certain medications: bile acid sequestrants such as cholestyramine/colestipol, mineral oil, orlistat.

Advice: Separate your doses of these medications as far as possible from your doses of Calcium + D3.

Adverse Effects

Constipation or stomach upset may occur with overdose.

Dosage & Administration

One tablet daily at meal with enough liquid. Do not chew.

Do not exceed the stated recommended daily dosage.

Food supplements should not be used as a substitute for a varied diet.

  • Lactose and gluten-free.

Storage/Handling Recommendations

Store below 25˚C. Keep away from direct sunlight.

Keep out of the reach of children.

Review Date

2017-09-15 10:17:42