No. 22, Abimbola Street, Isolo Industrial Estate, Isolo, P.O. Box 1647, Lagos, Nigeria.
Afrab Chem Ltd, 22 Abimbola Street, Isolo Industrial Estate, Isolo, Lagos.
Dosage Form, Composition & NAFDAC Registration Number (NRN)
Suspension (NRN:04-0211): When prepared as directed each 5 mL (teaspoonful) contains Ampicillin Trihydrate BP equivalent to 125 mg Ampicillin.
Pack Size: Bottle of 100 mL.
Ampicillin is a semisynthetic compound derived from 6-Amino-penicillanic acid. it has bactericidal action against Gram positive micro organisms of Streptococcus pneumoniae and other Streptococci, Enterococcus faecalis, it also has bactericidal action against Gram negative bacilli including some strain of Bordetella pertusis, Haemophillus influenza and some Enterobacteriaceae, such as E.coli, Proteus mirabillis, Salmonella and Shigella sp.
Ampicillin having an amino group attached to the basic Penicillin structure enables the drug penetrate the outer membrane of the micro organism.
Ampicillin is used in the treatment of a variety of infections due to susceptible organisms including Respiratory Tract infection, Urinary Tract infection, Gonorrhea, enteric infection, Meningitis and Septicaemia.
It is also useful in the treatment of Enteric fever, infection of the billiary tract, ear, nose, throat and soft tissue.
Susceptibility test should be carried out before initiating treatment to guard against resistance to the antibiotic caused by some beta-lactamase producing organisms.
The use of Ampicillin is contra-indicated in cases of hypersensitivity to ampicillin or other beta-lactam antibiotics.
To be used strictly under medical supervision in pregnancy.
Reduce dosage in case of renal impairement.
Interactions with other Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Nausea, diarrhoea, indigestion and rashes could occur.
Dosage & Administration
Preparation: Add 74 mL previously boiled and cooled water. Shake to obtain Suspension and use within one week of preparation
|Children 2.5-5 mL (62.5-125 mg) every 6 hours|
|2-6 years||5-10 mL (125-250 mg) every 6 hours|
|6-12 years||10-20 mL (250-500 mg) every 6 hours|
Keep in a cool dry place and away from the reach of Children.