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Hospimox

Afrab-Chem Ltd
No. 22, Abimbola Street, Isolo Industrial Estate, Isolo, P.O. Box 1647, Lagos, Nigeria.
Email: info@afrabchem.com
Tel: 234-1-2700057
Fax: 234-1-4520328
Website: http://afrabchem.com/

Brand Name

Hospimox

Manufacturer

Afrab Chem Ltd, 22 Abimbola Street, Isolo Ind. Estate, Isolo, Lagos

Therapeutic Class

Antibacterial, Penicillins

Dosage Form, Composition & NAFDAC Registration Number (NRN)

Capsule (NRN: 04-2339):Amoxycillin USP 500 mg.

Pack size:

 

Suspension (NRN: 04-2338):Amoxycillin trihydrate equivalent to Amoxycillin USP 125 mg per 5 mL.

How to identify the Product: Dry powder for oral syrup.

Pack size: 100 mL.

hospimox

Suspension (NRN: 04-2337):Amoxycillin trihydrate equivalent to Amoxycillin USP 250 mg per 5 mL.

How to identify the Product: Dry powder for oral syrup.

Pack size: 100 mL.

Pharmacology

Amoxicillin is similar to ampicillin in its bactericidal action against susceptible organisms during the stage of active multiplication. It acts through the inhibition of biosynthesis of cell wall mucopeptide. Amoxicillin has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections.

Amoxycillin is a broad spectrum antibiotic which exerts a bactericidal action against a wide variety of gram-positive and gram-negative bacterial pathogens including Streptococci, Pneumcocci, non-penicillinase producing Staphylococci, N. gonorrhoea, H. Influenzae, E. coli, Proteus mirabilis and other susceptible organisms. Amoxycillin is stable in the presence of gastric acid and well absorbed from the GIT.

Indications

Respiratory tract infections; ENT infections; Otitis media; Acute and Chronic bronchitis, Lobar and Broncho-pneumonia; Gynaecological infections including puerperal sepsis and septic abortion; Gonorrhea, Syphilis, Peritonitis, Meningitis, Intra-abdominal sepsis, Septicaemia, Bacteria endocarditis, typhoid and parathyphoid fever, Skin and Soft tissue infections, Enteric fever, Dental prophylaxis and Osteomyelitis.

Therapy may be instituted prior to obtaining results from bacteriological and susceptibility tests to Amoxycillin.

Contra-indications

Hypersensitivity to penicillins or other beta-lactam antibiotics.

Precautions/Warnings

Amoxycillin may cause reactions typical of penicillin allergy, especially in sensitive patients. In case of any allergic reactions, the drug should be discontinued and the patient is to be treated with the usual agents like antihistamines, pressor amines, and/or corticosteroids.

Interactions

Major interaction is with Methotrexate. So consult your healthcare practitioner if you are using other drugs.

Adverse Effects

Diarrhoea, indigestion, or occasionally rash, either urticarial, which suggests penicillin hypersensitivity, or erythematous rash which may be caused in patients with glandular fever, in which case it is advisable to discontinue the therapy.

Dosage & Administration

To be administered orally:

 Indications   Adults   Children   Duration 
 Respiratory Tract Infections      Every 8 hours  
 Skin and softtissue infections  250 mg  125 mg
 Nose, Throat & Ear Infections  500 mg  250 mg
 Gynaecological Infections    
 Acute Gonorrhea Infections  3000 mg

plus

 1500 mg

plus

 As a single Dose
 Ano-genital infections               1000 mg 500 mg
 Urethral Infections  Probenecid  Probenecid

Preparation: Add 75-80 mL of previously boiled and cooled water, or upto the indicated mark on the bottle and shake very well to obtain the suspension. Use within 7 days of reconstitution.

Storage/Handling Recommendations

Do not freeze, but keep in a cool dry place.

Review Date

2017-09-30 03:42:11