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Tovital

Biomedicine Sckivs Pharmaceuticals Nig. Ltd
3 Anionwu Street Odoakpu. P.O.Box 7846 Onitsha, Nigeria
Email: sckivspharm@yahoo.com
Tel: 234-0803-507-8844; 803-619-3742

Brand Name

Tovital

Manufacturer

Manufactured by: Softgel Healthcare Pvt. Ltd., Survey No. 20/1, Vandalur- Kelambakkam Road, Pudupakkam Village, Kancheepuram District, Tamilnadu -603103, India

Therapeutic Class

Vitamins

Dosage Form, Composition & NAFDAC Registration Number (NRN)

Capsule (NRN: ): Composition Each soft gelatin capsule contains: Vitamin E USP 1000IU (as dl-Alpha Tocopheryl acetate) Excipients q.s. Pack Size: TOVITAL 1000 available as 10 capsules in a blister and 3 such blisters are packed in a carton.

Pharmacology

Pharmacodynamic Vitamin E deficiency has been linked to disorders such as cystic fibrosis where fat absorption is impaired life essential for the normal function of the muscular system and the blood. Pharmacokinetics Vitamin E is absorbed from the gastro-intestinal tract. Most appears in the lymph and is then widely distributed to all tissues. Most of a dose is slowly excreted in the bile and the remainder is eliminated in the urine as glucuronides of tocopheronic acid or other metabolites

Indications

Indication Vitamin E is necessary in small amounts and is available in common foodstuffs like green leafy vegetables. Vitamin E prevents chemical oxidation. hence it acts mainly as an antioxidant. It is also important for the proper function of nerves and muscles. Vitamin E requirements are increased in intestinal disease, hepatic disease, pancreatic disorders and surgical removal of stomach. Prolonged treatment with vitamin E increases the survival time of erythrocytes in G-6-PD deficiency. The risk of retrolental fibroplasia in infants exposed to high concentrations of oxygen can be reduced by oral vitamin E.

Contra-indications

Contraindication Vitamin E may be contraindicated in bleeding disorders.

Precautions/Warnings

Warnings & Precautions Tell your doctor about your medical history. especially of: allergies (including sulpha drugs), diabetes, high blood cholesterol or fats (lipids), liver or kidney disorders, blood disorders (haemophilia), digestive disorders (malabsorption). Caution is advised when this drug is used in the elderly as this group may be more prone to drug side effects. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Avoid breast-feeding because breast milk can transmit HIV. Consult your doctor or pharmacist for more information.

Interactions

Drug interactions Vitamin E may impair the absorption of Vitamin A. Pregnancy and Lactation Trials have been conducted in pregnant women. The majority of trials report no increase in negative fetal outcome, but results regarding birth-weight are conflicting. Considering the evidence of harm (all-cause mortality), high-dose vitamin E supplementation should be used with caution. Natural food sources are preferred.

Adverse Effects

Undesirable effects Overdoses (>1g) have been associated with minor side effects, including hypertension, fatigue, diarrhoea and myopathy.

Dosage & Administration

Recommended dose Take one soft gel capsule daily with meals or as directed by the physician. Overdose and treatment Symptoms of overdose may include nausea, weakness, intestinal cramps, headache, flatulence, diarrhoea, drowsiness, or loss of consciousness

Storage/Handling Recommendations

Storage condition Store below 30

Review Date

2018-01-10 08:54:38